WCRPL 2017 Preliminary Scientific Program, as of January 2017

 Thursday,  19 January 2017
08:15-08:45 Opening Ceremony & Welcome Words
Asher Bashiri (Israel), William Kutteh (USA), Michael Sherf (Israel)
08:45-11:00 Session I. Epidemiological Aspects, Evidence Based Medicine
Chairs: Asher Bashiri (Israel) and William Kutteh (USA)
08:45-09:30 Recurrent Pregnancy Loss – Overview and Endocrine Aspects
Asher Bashiri (Israel)
09:30-10:00 Impact of Consecutive versus Non-Consecutive Miscarriages in RPL
Ole Christiansen (Denmark)
10:00-10:30 Progress on Standardized Outcomes for RPL Studies
James Scott (USA)
10:30-1100 The BMI and the Risks for RPL
Naama Steiner (Israel)
11:00-11:15 Coffee Break
11:15-13:45 Session II. Immunology
Chairs: Bettina Toth (Austria) and Ole Christiansen (Denmark)
11:15-11:45 Immunology in RPL: Facts and Fiction
Bettina Toth (Austria)
11:45-12:15 HLA-DR and -DQ (2000 patients) in RPL in the Danish Population
Catherine Thompson (Denmark)
12:15-12:45 Lymphocyte Immunization Therapy in Recurrent Pregnancy Loss – Is There a Place for This Treatment?
Alric Mondragon (Philippines)
12:45-13:15 Immunologic Processes at the Feto-Maternal Interphase
Udo Markert (Germany)
13:15-13:45 Immunologic Treatment Option, Cons and Pros
Bettina Toth (Austria) and Ole Christiansen (Denmark)
13:45-14:45 Lunch Break / Poster / Exhibition
14:45-17:45 Oral Communications I: Epidemiology, Immunology, Thrombophilia and RPL
Chairs: Asher Bashiri (Israel) and James Scott (USA)
14:45 Evaluating the Role of Vitamin D3 in Recurrent Miscarriage, a Narrative Systematic Literature Review
Noemi Hughes2, Lukasz Polanski1, Miriam Baumgarten1
1obs and gyn, Cambridge University Hospitals NHS trust, Addenbrookes, UK
2School of Medicine, University of Cambridge, UK
14:57 Does Ethnicity Influence Maternal and Pregnancy Characteristics in Women Experiencing Recurrent Pregnancy Loss?
Efrat Spiegel1, Avraham Harlev1, Naama Steiner1, Revital Djaoui Ben- Yaakov1, Michael Friger2, Ruslan Sergienko2, Asher Bashiri1
1Department of Obstetrics and Gynecology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel
2Department of Epidemiology and Health Services Evaluation, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva,, Israel
15:09 Thrombophilia Gene Mutations in Georgian Women with Recurrent Pregnancy Loss (RPL)
Jenaro Kristesashvili1,2, Nino Kochiashvili4, Nino Pirtskhelani3,4, Ketevan Kartvelishvili3,4, Maia Janelidze5, Madlena Khvichia5, Maia Jashiashvili2
1Obstetric, Gynecology, Reproductology, I.Javakhishvili Tbilisi State University, Georgia
2Pregnancy Loss Management, Center for Reproductive Medicine Universe, Georgia
3Genetics, Tbilisi State Medical University, Georgia
4Forensic Biology (DNA), National Forensics Bureau of Georgia, Georgia
5Obstetric, Gynecology, IQ-Clinic, Georgia
15:21 Decidual Th1/Th2&NK1/NK2 Phenotyping with 8-color Flowcytometry in Recurrent Miscarriage
Peng Dong1, Jian Li2
1Obstetrics and Gynecology Department, Xuan Wu Hospital, Capital Medical University, China
2Family Planning Department, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, China
15:33 Clinical and Immunologic Profile of Women with Recurrent Pregnancy Losses in a Tertiary Hospital in the Philippines
Alric V. Mondragon, Maria Socorro Agcaoili-de Jesus, Lara Theresa Alentajan-Aleta
Section of Allergy and Immunology, University of the Philippines – Philippine General Hospital, Philippines
15:45 Identification of Immunological Biomarkers for Recurrent Pregnancy Loss
Kwang-Hyun Baek1, Lan Li1, Jung-Hyun Park1, Bum-Chae Choi2, Yong Won Shin2
1Department of Biomedical Science, CHA University, CHA General Hospital, South Korea
2Department of Obstetrics and Gynecology, CL Womens Hospital, South Korea
15:57 An Immunological Profile is Associated with Development of Clinical Abnormalities in Women with Recurrent Pregnancy Loss
Javier Carbone, Elizabeth Sarmiento, Juan Paulo Navarro, Eduardo Fernandez-Cruz
Clinical Immunology, Hospital General Universitario Gregorio Maranon. Madrid, Spain
16:09 Analysis of CD138+ Uterine Plasma Cells in Patients with Recurrent Miscarriage
Kilian Vomstein1, Ruben Kuon1, Tamara Goeggl1, Maja Weber2, Udo Markert2, Thomas Strowitzki1, Bettina Toth3
1Department of Gynecological Endocrinology and Fertility Disorders, Ruprecht-Karls University Heidelberg, INF 440, 69120 Heidelberg, Germany
2Placenta-Lab, Department of Obstetrics, University Hospital Jena, Bachstrasse 18, 07743 Jena, Germany
3Department of Gynecological Endocrinology and Reproductive Medicine, University of Innsbruck, Austria, Germany
16:21 Higher Incidence of Colonization with Gardnerella Vaginalis in Patients with Recurrent Miscarriage and Elevated Peripheral Natural Killer Cells
Ruben Kuon1, Riku Togawa1, Kilian Vomstein1, Tamara Goeggl1, Thomas Strowitzki1, Volker Daniel2, Alexander Dalpke3, Bettina Toth1
1Department of Gynecological Endocrinology and Fertility Disorders, University Hospital Heidelberg, Germany
2Department of Transplant Immunology, University Hospital Heidelberg, Germany
3Department of Infectious Diseases, Medical Microbiology, University Hospital Heidelberg, Germany
16:33 Characteristics of Subsequent (Index) Pregnancy in Women Experiencing Recurrent Pregnancy Loss
Naama Steiner1, Avi Harlev1, Efrat Spiegel1, Revital Djaoui Ben- Yaakov1, Ruslan Serjienko2, Asher Bashiri1
1Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel
2Department of Epidemiology and Health Services Evaluation, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel
16:45 G-CSF Treatment in Unexplained Recurrent Pregnancy Loss: Results of a Controlled Trial on 120 Women and Total Data on Ten Years Experience
Fabio Scarpellini1, Avenir Balili2, Marco Sbracia1
1IVF CENTER, CERM-HUNGARIA, Italy
2GYNECOLOGY OBSTETRICS, TIRANA STATE UNIVERSITY, Albania
16:57 A 9-year Retrospective Analysis of Associated Medical Conditions in a Tertiary Level Recurrent Miscarriage Clinic in Cape Town, South Africa – Is BMI the Tip of the Iceberg in RM?
Mushi Matjila, Anne Hoffman, Zephne van der Spuy
Department of Obstetrics and Gynaecology, Groote Schuur Hospital and University Of Cape Town, Cape Town, 7937, South Africa
17:45-18:45 Welcome Reception
 Friday, 20 January 2017
08:00-10:30 Session III. Infertility
Chairs: Raoul Orvieto (Israel) and Eitan Lunenfeld (Israel)
08:00-08:30 The Continuing Spectrum of Infertility and RPL
Mala Arora (India)
08:30-09:00 Recurrent Implantation Failure
Eitan Lunenfeld (Israel)
09:00-09:30 The Role of Oxidative Stress and Anti-Oxidants Treatment in (Unexplained?) RPL
Avraham Harlev (Israel)
09:30-10:00 Metformin – Old News? Does Metformin Prevent Miscarriages in PCOS Patients?
Raoul Orvieto (Israel)
10:00-10:30 To select or Not to Select – The Role of Sperm Selection Techniques in RPL Prevention
Avraham Harlev (Israel)
10:30-11:00 Coffee Break / Posters / Exhibition
11:00-13:30 Session IV. Anatomy
Chairs: Mala Arora (India) and Olivier Toullalan (France)
11:00-11:30 Anatomical Causes of RPL, the Role of 3D Ultrasound and the Significance of Determining Fetal Abnormalities
Asher Bashiri (Israel)
11:30-12:00 Endoscopic Septectomy for RPL Patients
Arsen Gvenetadze (Georgia)
12:00-12:30 Late Pregnancy Loss
Bruce Young (USA)
12:30-13:00 The Role of Hystero-Embryoscopy in the Management of RPL
Vasilios Tanos (Cyprus)
13:00-13:30 Cervical Incompetence Evaluation and Management
Salim Daya (Canada)
13:30-14:30 Lunch Break / Posters / Exhibition
14:30-15:00 Industry Supported Session
not included in main event CME/CPD credit
15:00-17:00 Session V. Thrombophilia
Chairs: Avraham Harlev (Israel) and Alric Mondragon (Philippines)
15:00-15:30 Guidelines for Evaluation Hereditary Thrombophilia among Patients with Recurrent Pregnancy Loss and New Diagnostic Test
Asher Bashiri (Israel)
15:30-16:00 APLA Syndrome and RPL
William Kutteh (USA)
16:00-16:30 Treatment Options in Refractory Obstetric Antiphospholipid Syndrome
Alric Mondragon (Philippines)
16:30-17:00 Is Aspirin a Treatment for RPL?
Howard Carp (Israel)
  Saturday, 21 January 2017
08:00-10:30 Session VI. Genetics
Chairs: Elias Dahdouh (Canada) and Vasilios Tanos (Cyprus)
08:00-08:30 Genetic Factors in Recurrent Pregnancy Loss
Sally Rodriguez (USA)
08:30-09:00 Molecular Analysis of Chromosomal Abnormalities in Products of Conception (POCs)
Carmen Rubio (Spain)
09:00-09:30 Embryoscopy in Unexplained Recurrent Spontaneous Abortions Correlation of Embryo Morphology and Karyotype
Vasilios Tanos (Cyprus)
09:30-10:00 PGD/PGS in RPL: Is It Really Beneficial?
Elias Dahdouh (Canada), challenged by William Kutteh (USA)
10:00-10:30 Case Presentations and Panel Discussion
All session speakers
10:30-11:00 Coffee Break / Posters / Exhibition
11:00-12:30 Session VII. Psychological and Organizational Support
Chairs: Bruce Young (USA) and Arsen Gvenetadze (Georgia)
11:00-11:30 Pregnancy Loss Prevention Center: Clinical Experience
Bruce Young (USA)
11:30-12:00 Learning to stay with what is: Mindfulness training as a way to enhance stress management, acceptance and compassion due to recurrent pregnancy loss.
Oded Arbel (Israel)
12:00-12:30 How to Organize an RPL Clinic
Ole Christiansen (Denmark)
12:30-13:30 Lunch Break / Posters/ Exhibition
13:30-16:00 Oral Communications II: Anatomy, Genetics and Fertility
Chairs: William Kutteh (USA) and Elias Dahdouh (Canada)
13:30 Pregnancy Outcomes in Women with Recurrent Miscarriages Following Endometrial Biopsy- a Systematic Review of Literature
Lukasz Polanski, Norman Shreeve, Miriam Baumgarten
Obstetrics and Gynaecology, Addenbrooke’s Hospital, UK
13:42 Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) does not Improve Miscarriage Rate for Patients with Recurrent Implantation Failure and/or Male Factor Infertility
Montserrat Duran Retamal, Srividya Seshadri, Kalliopi Loutradi, Paul Serhal, Alpesh Doshi, Wael Saab, Suzanne Cawood
CRGH, The Centre for Reproductive and Genetic Health, UK
13:54 The Value of Three-dimensional Ultrasound in Diagnosis of Congenital Uterine Anomalies
Tamari Arkania, Arsen Gvenetadze
Radiology, Reproductive Clinic of Zurab Sabakhtarashvili, Georgia
14:06 Anti-P Allo-Antibodies as a Cause for Recurrent Early Miscarriages & Late Pregnancy Loss
Ido Solt1, Zeev Weiner1, Eldad J Dan2, Lilach Bonshtein2
1Obsterics and Gynecology, Rambam Health Care Campus, Haifa, Israel
2Blood Bank and platelet & Neutrophil Immunology laboratories, Rambam Health Care Campus, Haifa, Israel
14:18 The Genome-Wide Association Study Identifying TSHR and C1d as New Susceptibility Loci for Obstetric Antiphospholipid Syndrome
Mayumi Sugiura-Ogasawara1, Yosuke Omae2, Minae Kawashima2, Licht Toyo-oka2, Seki-Soon Khor2, Hiromi Sawai2, Tetsuya Horita3, Atsumi Tatsuya3, Atsuko Murashima4, Tamao Kitaori1, Kinue Katano1, Yasuhiko Ozaki1, Katsushi Tokunaga2
1Obstetric and Gynecology, Nagoya City University, Graduate School of Medical sciences, Japan
2Human Genetics, Graduate School of Medicine, The University of Tokyo, Japan
3Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Japan
4Center for Maternal-Fetal-Neonatal and Reproductive Medicine, National Center for Child Health and Development, Japan
14:30 Recurrent Pregnancy Loss and Antiphospholipde Syndrome
Aleksandar Stefanovic, Katarina Jeremic, Jelena Dotlic, Sasa Kadija, Miroslava Gojnic Dugalic, Milena Mitrovic
Ob/Gyn, Clinic of Obstetrics and Gynecology, Clinical Center of Serbia, Medical Faculty University of Belgrade, Serbia
14:42 Unraveling the Diverse Landscape of Genomic Abnormalities from Conception to Childhood
Trilochan Sahoo, Michelle N Strecker, Natasa Dzidic, Sara B Commander, Mary K Travis, Karine Hovanes
Cytogenetics and Genomics, CombiMatrix Diagnostics, USA
14:54 Balanced Structural Chromosomal Anomalies in Couples with Recurrent Pregnancy Loss (RPL)
Jenaro Kristesashvili1,2, Nino Sigua3, Maia Rukhadze3, Marina Mdivnishvili2, Natela Jangulashvili3
1Obstetric, Gynecology, Reproductology, I.Javakhishvili Tbilisi State University, Medical Faculty, Georgia
2Pregnancy Loss Management, Center for Reproductive Medicine Universe, Georgia
3Genetics, Georgian Centre of Prenatal Diagnostics, Georgia
15:06 A Meta-analysis of Low-Molecular Weight Heparin to Prevent Pregnancy Loss in Women with Inherited Thrombophilia
Risto Kaaja1, Leslie Skeith2, Marc Carrier2, Ida Martinelli3, David Petroff4, Ekkehard Schleussner5, Carl A Laskin6, Marc A Rodger2
1Internal Medicine, University of Turku, Turku University Hospital, Finland
2Department of Medicine, University of Ottawa and the Ottawa Hospital, Canada
3A. Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione Istituto di Ricovero e Cura a Carattere, Italy
4Clinical Trial Center, University of Leipzig, Germany
5Obstetrics and Gynecology, Friedrich Schiller University Hospital, Germany
6Medicine and Obstetrics and Gynecology, University of Toronto, Canada
15:18 The Contribution of Fertility Treatments to Pregnancy Outcome in Patients with Recurrent Pregnancy Loss
Revital Djaoui Ben Yaakov1, Avraham Harlev1, Efrat Spiegel1, Naama Steiner1, Michael Friger2, Ruslan Sergienko2, Asher Bashiri1
1Department of Obstetrics and Gynecology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel
2Department of Epidemiology and Health Services Evaluation, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel
15:30 Deficiency of Placental Copy Number Variations in Recurrent Pregnancy Loss Patients
Laura Kasak1, Kristiina Rull1,2, Maris Laan1
1Human Molecular Genetics Research Group, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia
2Department of Obstetrics and Gynaecology, University of Tartu, Tartu, Estonia
15:42 Application of Thrombelastography to Monitor The Change of Coagulation Function in Patients of Recurrent Spontaneous Abortion with Different Times Miscarriages Before and After Pregnancy
Kang Danyang, Hou Yue, Qiao Chong
Department of Obstetrics and Gynecology, ShengJing Hospital, China Medical University, China
16:00-16:15 Short Break
16:15-18:15 Stop, Sit, Breath, Let It Be – Experiential Workshop in Mindfulness
Oded Arbel (Israel)
Registration is required.
Sunday, 22 January 2017
08:00-10:00 Meet the Expert Session
Interactive session with the audience, case presentations
Moderator: Asher Bashiri (Israel)
Arsen Gvenetadze (Georgia), Avraham Harlev (Israel)Alric Mondragon (Philippines), James Scott (USA), Vasilis Tanos (Cyprus), Bruce Young (USA)
10:00-12:00 Oral Communications III: Different Aspects of RPL
Chairs: Bruce Young (USA) and Avraham Harlev (Israel)
10:00 Prevalence of Vitamin D Levels in the Recurrent Pregnancy Loss Population
Noemi Hughes2, Lukasz Polanski1, Miriam Baumgarten1
1Obs and Gyn, Cambridge University Hospitals NHS trust, Addenbrookes Hosp, UK
2Medicine, University of Cambridge, UK
10:12 Mechanisms of Action of G-CSF Treatment in Recurrent Pregnancy Loss: Immunological and Trophoblast Growth Pathways
Marco Sbracia1, Avenir Balili2, Fabio Scarpellini1
1IVF Center, Cerm-Hungaria, Italy
2Gynecology Obstetrics, Tirana State University, Albania
10:24 Evil Eye, Stress and Overwork: Theories of Miscarriage Causations among Qatari Women
Nadia Omar1, Stella Major1, Susie Kilshaw3, Faten El Taher2, Mona Mohsen1, Halima Al Tamimi2, Kristina Sole1, Daniel Miller3
1Family Medicine, Weill cornell Medical college- Qatar, Qatar
2Women’s hosptial, Hamad Medical coorporation, Qatar
3Medical Anthropology, University College London, UK
10:36 Pregnancy Outcomes in the Recurrent Miscarriage Clinic – Is One Scan Sufficient?
Laura Hume1, James Walker1,2, Jayne Shillito1
1Obstetrics and Gynaecology, Leeds Teaching Hospitals Trust, UK
2School of Medicine, University of Leeds, UK
10:48 A New Exclusive Innovation Model of Obstetrical Pessary – Prevention and Treatment of Cervical Insufficiency and Habitual Abortion
Schneiderman Mikhail
Moscow, FSBI Kulakov Federal Research Center for Obstetrics, Gynecology and Perinatology, Russia
11:00 Tendencies of Depression and Anxiety are Highly Prevalent among Women with Recurrent Pregnancy Loss and Infertility
Liana Barabadze, Arsen Gvenetadze
Reproductive Clinic of Zurab Sabakhtarashvili, Georgia
11:12 RNA-Seq Analysis of Chorionic Villi from Recurrent Pregnancy Loss Cases Compared to Normal Early Pregnancy
Siim Sõber1, Kristiina Rull1,3,4, Mario Reiman1, Piret Ilisson5, Pirkko Mattila6,7, Maris Laan1,2
1Institute of Molecular and Cell Biology, University of Tartu, Estonia
2Institute of Biomedicine and Translational Medicine, University of Tartu, Estonia
3Department of Obstetrics and Gynaecology, University of Tartu, Estonia
4Women’s Clinic, Tartu University Hospital, Estonia
5Department of Genetics, United Laboratories, Tartu University Hospital, Estonia
6Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Finland
7Blood Service, Finnish Red Cross, Finland
11:24 Low Molecular Weight Heparin (LMWH): Enoxaparin as Adyuvant of in Vitro Fertilization Techniques (IVF) in Women with Recurrent Implantation Failures (RIF): Obstetric and Perinatal Outcome: Preliminary Report
Beatriz Grand1, Marcos Horton2, Alejandro Oubiña2, Ignacio De Zuñiga2, Marcelo Garcea2, Guillermo Terrado2, Laura Kopcow2, Fabio Sobral2
1Hematologia, Consultorios, Argentina
2Medicina Reproductiva, PREGNA, Argentina
12:00-12:10 Closing Remarks